1o5d | pdb_00001o5d
From Proteopedia
Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)
Disease
Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]
About this Structure
1O5D is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Katz BA, Luong C, Ho JD, Somoza JR, Gjerstad E, Tang J, Williams SR, Verner E, Mackman RL, Young WB, Sprengeler PA, Chan H, Mortara K, Janc JW, McGrath ME. Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA). J Mol Biol. 2004 Nov 19;344(2):527-47. PMID:15522303 doi:10.1016/j.jmb.2004.09.032
Page seeded by OCA on Mon Feb 16 16:22:40 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Coagulation factor VIIa
- Homo sapiens
- Chan, H.
- Gjerstad, E.
- Ho, J D.
- Janc, J W.
- Katz, B A.
- Luong, C.
- Mackman, R L.
- McGrath, M E.
- Mortara, K.
- Somoza, J R.
- Sprengeler, P A.
- Tang, J.
- Verner, E.
- Williams, S R.
- Young, W B.
- Ala190 upa
- Conserved water displacement hydrogen bond deficit
- Factor viia
- Hepsin
- S1 site
- Selectivity
- Thrombin
- Trypsin
