1tlc | pdb_00001tlc

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File:1tlc.png

Template:STRUCTURE 1tlc

THYMIDYLATE SYNTHASE COMPLEXED WITH DGMP AND FOLATE ANALOG 1843U89

Template:ABSTRACT PUBMED 7724588

About this Structure

1TLC is a 2 chains structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  1. Weichsel A, Montfort WR, Ciesla J, Maley F. Promotion of purine nucleotide binding to thymidylate synthase by a potent folate analogue inhibitor, 1843U89. Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3493-7. PMID:7724588

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