2pzr | pdb_00002pzr

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Template:STRUCTURE 2pzr

File:2pzr.png

Crystal Strucure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K641R Mutation Responsible for Pfeiffer Syndrome

Template:ABSTRACT PUBMED 17803937

About this Structure

2PZR is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Chen H, Ma J, Li W, Eliseenkova AV, Xu C, Neubert TA, Miller WT, Mohammadi M. A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol Cell. 2007 Sep 7;27(5):717-30. PMID:17803937 doi:https://dx.doi.org/10.1016/j.molcel.2007.06.028

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