2vx1 | pdb_00002vx1

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File:2vx1.png

Template:STRUCTURE 2vx1

EPHB4 KINASE DOMAIN INHIBITOR COMPLEX

Template:ABSTRACT PUBMED 18434142

About this Structure

2VX1 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Bardelle C, Cross D, Davenport S, Kettle JG, Ko EJ, Leach AG, Mortlock A, Read J, Roberts NJ, Robins P, Williams EJ. Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines. Bioorg Med Chem Lett. 2008 May 1;18(9):2776-80. Epub 2008 Apr 10. PMID:18434142 doi:10.1016/j.bmcl.2008.04.015

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