2c2k | pdb_00002c2k

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Template:STRUCTURE 2c2k

File:2c2k.png

CRYSTAL STRUCTURES OF CASPASE-3 IN COMPLEX WITH AZA-PEPTIDE MICHAEL ACCEPTOR INHIBITORS.

Template:ABSTRACT PUBMED 16970398

About this Structure

2C2K is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Ekici OD, Li ZZ, Campbell AJ, James KE, Asgian JL, Mikolajczyk J, Salvesen GS, Ganesan R, Jelakovic S, Grutter MG, Powers JC. Design, synthesis, and evaluation of aza-peptide Michael acceptors as selective and potent inhibitors of caspases-2, -3, -6, -7, -8, -9, and -10. J Med Chem. 2006 Sep 21;49(19):5728-49. PMID:16970398 doi:https://dx.doi.org/10.1021/jm0601405

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