1v1k | pdb_00001v1k

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Template:STRUCTURE 1v1k

File:1v1k.png

CDK2 IN COMPLEX WITH A DISUBSTITUTED 4, 6-BIS ANILINO PYRIMIDINE CDK4 INHIBITOR

Template:ABSTRACT PUBMED 12941311

About this Structure

1V1K is a 1 chain structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1h06. Full crystallographic information is available from OCA.

Reference

  1. Beattie JF, Breault GA, Ellston RP, Green S, Jewsbury PJ, Midgley CJ, Naven RT, Minshull CA, Pauptit RA, Tucker JA, Pease JE. Cyclin-dependent kinase 4 inhibitors as a treatment for cancer. Part 1: identification and optimisation of substituted 4,6-bis anilino pyrimidines. Bioorg Med Chem Lett. 2003 Sep 15;13(18):2955-60. PMID:12941311

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