2hsq | pdb_00002hsq

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File:2hsq.png

Template:STRUCTURE 2hsq

Human vinculin (head domain, Vh1, residues 1-258) in complex with Shigella's IpaA vinculin binding site 2 (residues 565-587)

Template:ABSTRACT PUBMED 17088427

Disease

Known disease associated with this structure: Cardiomyopathy, dilated, 1W OMIM:[193065]

About this Structure

2HSQ is a 2 chains structure of sequences from Homo sapiens and Shigella flexneri. Full crystallographic information is available from OCA.

Reference

  1. Izard T, Tran Van Nhieu G, Bois PR. Shigella applies molecular mimicry to subvert vinculin and invade host cells. J Cell Biol. 2006 Nov 6;175(3):465-75. PMID:17088427 doi:https://dx.doi.org/10.1083/jcb.200605091

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