2vki | pdb_00002vki
From Proteopedia
STRUCTURE OF THE PDK1 PH DOMAIN K465E MUTANT
About this Structure
2VKI is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bayascas JR, Wullschleger S, Sakamoto K, Garcia-Martinez JM, Clacher C, Komander D, van Aalten DM, Boini KM, Lang F, Lipina C, Logie L, Sutherland C, Chudek JA, van Diepen JA, Voshol PJ, Lucocq JM, Alessi DR. Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance. Mol Cell Biol. 2008 May;28(10):3258-72. Epub 2008 Mar 17. PMID:18347057 doi:10.1128/MCB.02032-07
Page seeded by OCA on Mon Feb 16 18:54:36 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Non-specific serine/threonine protein kinase
- Aalten, D M.F Van.
- Alessi, D R.
- Bayascas, J R.
- Deak, M.
- Komander, D.
- 3-phosphoinositide
- Alternative splicing
- Atp-binding
- Cancer
- Cytoplasm
- Diabetes
- Kinase
- Membrane
- Nucleotide-binding
- Pdk1
- Phosphorylation
- Pi3-kinase
- Pkb
- Pleckstrin homology
- Serine/threonine-protein kinase
- Transferase
