2cgn | pdb_00002cgn
From Proteopedia
FACTOR INHIBITING HIF-1 ALPHA WITH SUCCINATE
About this Structure
2CGN is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Hewitson KS, Lienard BM, McDonough MA, Clifton IJ, Butler D, Soares AS, Oldham NJ, McNeill LA, Schofield CJ. Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates. J Biol Chem. 2007 Feb 2;282(5):3293-301. Epub 2006 Nov 29. PMID:17135241 doi:10.1074/jbc.M608337200
Page seeded by OCA on Mon Feb 16 20:01:56 2009
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Categories:
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- Homo sapiens
- Peptide-aspartate beta-dioxygenase
- Clifton, I J.
- Mcdonough, M A.
- Schofield, C J.
- 2-oxoglutarate
- Acetylation
- Activator
- Alternative splicing
- Asparaginyl hydroxylase
- Dna-binding
- Dsbh
- Fi
- Hif
- Hydroxylation
- Hypoxia
- Nuclear protein
- Oxidoreductase
- Oxygenase
- Phosphorylation
- Polymorphism
- S-nitrosylation
- Transcription
- Transcription activator/inhibitor
- Transcription regulation