2gv6 | pdb_00002gv6

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Template:STRUCTURE 2gv6

File:2gv6.png

Crystal Structure of Matriptase with Inhibitor CJ-730

Template:ABSTRACT PUBMED 16821772

Disease

Known disease associated with this structure: Ichthyosis with hypotrichosis OMIM:[606797]

About this Structure

2GV6 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Steinmetzer T, Schweinitz A, Sturzebecher A, Donnecke D, Uhland K, Schuster O, Steinmetzer P, Muller F, Friedrich R, Than ME, Bode W, Sturzebecher J. Secondary amides of sulfonylated 3-amidinophenylalanine. New potent and selective inhibitors of matriptase. J Med Chem. 2006 Jul 13;49(14):4116-26. PMID:16821772 doi:10.1021/jm051272l

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