1ym4 | pdb_00001ym4

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Template:STRUCTURE 1ym4

File:1ym4.png

Crystal structure of human beta secretase complexed with NVP-AMK640

Template:ABSTRACT PUBMED 16078837

About this Structure

1YM4 is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Hanessian S, Yun H, Hou Y, Yang G, Bayrakdarian M, Therrien E, Moitessier N, Roggo S, Veenstra S, Tintelnot-Blomley M, Rondeau JM, Ostermeier C, Strauss A, Ramage P, Paganetti P, Neumann U, Betschart C. Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics. J Med Chem. 2005 Aug 11;48(16):5175-90. PMID:16078837 doi:10.1021/jm050142+

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