2uzw | pdb_00002uzw
From Proteopedia
PKA STRUCTURES OF INDAZOLE-PYRIDINE SERIES OF AKT INHIBITORS
About this Structure
2UZW is a 2 chains structure of sequences from Bos taurus. Full crystallographic information is available from OCA.
Reference
- Zhu GD, Gandhi VB, Gong J, Thomas S, Woods KW, Song X, Li T, Diebold RB, Luo Y, Liu X, Guan R, Klinghofer V, Johnson EF, Bouska J, Olson A, Marsh KC, Stoll VS, Mamo M, Polakowski J, Campbell TJ, Martin RL, Gintant GA, Penning TD, Li Q, Rosenberg SH, Giranda VL. Syntheses of potent, selective, and orally bioavailable indazole-pyridine series of protein kinase b/akt inhibitors with reduced hypotension. J Med Chem. 2007 Jun 28;50(13):2990-3003. Epub 2007 May 25. PMID:17523610 doi:10.1021/jm0701019
Page seeded by OCA on Mon Feb 16 20:57:54 2009
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Categories:
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- Bos taurus
- CAMP-dependent protein kinase
- Bouska, J.
- Campbell, T J.
- Diebold, R B.
- Gandhi, V B.
- Giranda, V L.
- Gong, J.
- Guan, R.
- Johnson, E F.
- Klinghofer, V.
- Li, Q.
- Li, T.
- Liu, X.
- Luo, Y.
- Mamo, M.
- Marsh, K C.
- Olson, A.
- Penning, T D.
- Polakowski, J.
- Rosenberg, S H.
- Song, X.
- Stoll, V S.
- Thomas, S.
- Woods, K W.
- Zhu, G D.
- Akt inhibitor
- Atp-binding
- Camp
- Kinase
- Lipoprotein
- Myristate
- Nuclear protein
- Nucleotide-binding
- Phosphorylation
- Protein kinase some
- Serine/threonine-protein kinase
- Transferase