2q8h | pdb_00002q8h

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File:2q8h.png

Template:STRUCTURE 2q8h

Structure of pyruvate dehydrogenase kinase isoform 1 in complex with dichloroacetate (DCA)

Template:ABSTRACT PUBMED 17683942

About this Structure

2Q8H is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Kato M, Li J, Chuang JL, Chuang DT. Distinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicol. Structure. 2007 Aug;15(8):992-1004. Epub 2007 Aug 2. PMID:17683942 doi:10.1016/j.str.2007.07.001

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