1a1b | pdb_00001a1b

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File:1a1b.png

Template:STRUCTURE 1a1b

C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE)

Template:ABSTRACT PUBMED 9174343

Disease

Known disease associated with this structure: Colon cancer, advanced OMIM:[190090]

About this Structure

1A1B is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Charifson PS, Shewchuk LM, Rocque W, Hummel CW, Jordan SR, Mohr C, Pacofsky GJ, Peel MR, Rodriguez M, Sternbach DD, Consler TG. Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry. 1997 May 27;36(21):6283-93. PMID:9174343 doi:https://dx.doi.org/10.1021/bi970019n

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