2rn5 | pdb_00002rn5

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Template:STRUCTURE 2rn5

File:2rn5.png

Humal Insulin Mutant B31Lys-B32Arg

Template:ABSTRACT PUBMED 18491415

Disease

Known disease associated with this structure: Diabetes mellitus, rare form OMIM:[176730], Hyperproinsulinemia, familial OMIM:[176730], MODY, one form OMIM:[176730]

About this Structure

2RN5 is a 2 chains structure of sequences from Homo sapiens. Full experimental information is available from OCA.

Reference

  1. Bocian W, Borowicz P, Mikolajczyk J, Sitkowski J, Tarnowska A, Bednarek E, Glabski T, Tejchman-Malecka B, Bogiel M, Kozerski L. NMR structure of biosynthetic engineered human insulin monomer B31(Lys)-B32(Arg) in water/acetonitrile solution. Comparison with the solution structure of native human insulin monomer. Biopolymers. 2008 Oct;89(10):820-30. PMID:18491415 doi:10.1002/bip.21018

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