2a0q | pdb_00002a0q

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File:2a0q.png

Template:STRUCTURE 2a0q

Structure of thrombin in 400 mM potassium chloride

Template:ABSTRACT PUBMED 15998637

Disease

Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this Structure

2A0Q is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Papaconstantinou ME, Carrell CJ, Pineda AO, Bobofchak KM, Mathews FS, Flordellis CS, Maragoudakis ME, Tsopanoglou NE, Di Cera E. Thrombin functions through its RGD sequence in a non-canonical conformation. J Biol Chem. 2005 Aug 19;280(33):29393-6. Epub 2005 Jul 5. PMID:15998637 doi:10.1074/jbc.C500248200

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