2oph | pdb_00002oph

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File:2oph.png

Template:STRUCTURE 2oph

Human dipeptidyl peptidase IV in complex with an alpha amino acid inhibitor

Template:ABSTRACT PUBMED 17350841

About this Structure

2OPH is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Duffy JL, Kirk BA, Wang L, Eiermann GJ, He H, Leiting B, Lyons KA, Patel RA, Patel SB, Petrov A, Scapin G, Wu JK, Thornberry NA, Weber AE. 4-aminophenylalanine and 4-aminocyclohexylalanine derivatives as potent, selective, and orally bioavailable inhibitors of dipeptidyl peptidase IV. Bioorg Med Chem Lett. 2007 May 15;17(10):2879-85. Epub 2007 Feb 25. PMID:17350841 doi:10.1016/j.bmcl.2007.02.066

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