2et2 | pdb_00002et2

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Template:STRUCTURE 2et2

File:2et2.png

Crystal structure of an Asn to Ala mutant of Winged Bean Chymotrypsin Inhibitor protein

Template:ABSTRACT PUBMED 16734415

About this Structure

2ET2 is a 1 chain structure of sequence from Psophocarpus tetragonolobus. Full crystallographic information is available from OCA.

Reference

  1. Dasgupta J, Khamrui S, Dattagupta JK, Sen U. Spacer Asn determines the fate of Kunitz (STI) inhibitors, as revealed by structural and biochemical studies on WCI mutants. Biochemistry. 2006 Jun 6;45(22):6783-92. PMID:16734415 doi:10.1021/bi060374q
  2. Khamrui S, Dasgupta J, Dattagupta JK, Sen U. Single mutation at P1 of a chymotrypsin inhibitor changes it to a trypsin inhibitor: X-ray structural (2.15 A) and biochemical basis. Biochim Biophys Acta. 2005 Aug 31;1752(1):65-72. PMID:16081330 doi:10.1016/j.bbapap.2005.06.012
  3. Dasgupta J, Sen U, Dattagupta JK. In silico mutations and molecular dynamics studies on a winged bean chymotrypsin inhibitor protein. Protein Eng. 2003 Jul;16(7):489-96. PMID:12915726

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