2v00 | pdb_00002v00
From Proteopedia
X-RAY CRYSTAL STRUCTURE OF ENDOTHIAPEPSIN COMPLEXED WITH COMPOUND 1
About this Structure
2V00 is a 1 chain structure of sequence from Cryphonectria parasitica. Full crystallographic information is available from OCA.
Reference
- Geschwindner S, Olsson LL, Albert JS, Deinum J, Edwards PD, de Beer T, Folmer RH. Discovery of a novel warhead against beta-secretase through fragment-based lead generation. J Med Chem. 2007 Nov 29;50(24):5903-11. Epub 2007 Nov 7. PMID:17985861 doi:10.1021/jm070825k
Page seeded by OCA on Tue Feb 17 01:21:00 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Cryphonectria parasitica
- Endothiapepsin
- Albert, J S.
- Beer, T De.
- Deinum, J.
- Edwards, P D.
- Folmer, R H.A.
- Geschwindner, S.
- Olsson, L L.
- Alzheimer's disease
- Aspartyl protease
- B- secretase
- Bace
- Fragment hit
- Fragment-based lead generation
- Hydrolase
- Isocytosine
- Protease
- Surrogate protein
- Zymogen
