1y8w | pdb_00001y8w

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Template:STRUCTURE 1y8w

File:1y8w.png

T-To-T(High) quaternary transitions in human hemoglobin: alphaR92A oxy (2mM IHP, 20% PEG) (10 test sets)

Template:ABSTRACT PUBMED 15835899

Disease

Known disease associated with this structure: Erythremias, alpha- OMIM:[141800], Heinz body anemias, alpha- OMIM:[141800], Methemoglobinemias, alpha- OMIM:[141800], Thalassemias, alpha- OMIM:[141800]

About this Structure

1Y8W is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Kavanaugh JS, Rogers PH, Arnone A. Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions. Biochemistry. 2005 Apr 26;44(16):6101-21. PMID:15835899 doi:https://dx.doi.org/10.1021/bi047813a

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