2rkp | pdb_00002rkp
From Proteopedia
Crystal structure of the catalytic subunit of human protein kinase CK2 with 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole
About this Structure
2RKP is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Raaf J, Brunstein E, Issinger OG, Niefind K. The CK2 alpha/CK2 beta interface of human protein kinase CK2 harbors a binding pocket for small molecules. Chem Biol. 2008 Feb;15(2):111-7. PMID:18291315 doi:https://dx.doi.org/10.1016/j.chembiol.2007.12.012
- Niefind K, Yde CW, Ermakova I, Issinger OG. Evolved to be active: sulfate ions define substrate recognition sites of CK2alpha and emphasise its exceptional role within the CMGC family of eukaryotic protein kinases. J Mol Biol. 2007 Jul 13;370(3):427-38. Epub 2007 May 5. PMID:17524418 doi:https://dx.doi.org/10.1016/j.jmb.2007.04.068
- Ermakova I, Boldyreff B, Issinger OG, Niefind K. Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit. J Mol Biol. 2003 Jul 25;330(5):925-34. PMID:12860116
Page seeded by OCA on Tue Feb 17 02:23:18 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Non-specific serine/threonine protein kinase
- Issinger, O G.
- Niefind, K.
- Raaf, J.
- Allosteric binding site
- Atp-binding
- Drb
- Eukaryotic protein kinase fold
- Human ck2alpha
- Nucleotide-binding
- Protein kinase ck2
- Protein kinase inhibitor complex
- Serine/threonine-protein kinase
- Transferase
- Wnt signaling pathway
