2guo | pdb_00002guo
From Proteopedia
Human Class I MHC HLA-A2 in complex with the native nonameric Melan-A/MART-1(27-35) peptide
Disease
Known disease associated with this structure: Abacavir hypersensitivity, susceptibility to OMIM:[142800], Ankylosing spondylitis, susceptibility to, 1 OMIM:[142800], Stevens-Johnson syndrome, susceptibility to OMIM:[142800], Hypoproteinemia, hypercatabolic OMIM:[109700]
About this Structure
2GUO is a 6 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Borbulevych OY, Insaidoo FK, Baxter TK, Powell DJ Jr, Johnson LA, Restifo NP, Baker BM. Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition. J Mol Biol. 2007 Oct 5;372(5):1123-36. Epub 2007 Jul 26. PMID:17719062 doi:10.1016/j.jmb.2007.07.025
Page seeded by OCA on Tue Feb 17 04:00:05 2009
