2v1y | pdb_00002v1y
From Proteopedia
STRUCTURE OF A PHOSPHOINOSITIDE 3-KINASE ALPHA ADAPTOR-BINDING DOMAIN (ABD) IN A COMPLEX WITH THE ISH2 DOMAIN FROM P85 ALPHA
About this Structure
2V1Y is a 2 chains structure of sequences from Bos taurus and Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Miled N, Yan Y, Hon WC, Perisic O, Zvelebil M, Inbar Y, Schneidman-Duhovny D, Wolfson HJ, Backer JM, Williams RL. Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit. Science. 2007 Jul 13;317(5835):239-42. PMID:17626883 doi:317/5835/239
Page seeded by OCA on Tue Feb 17 04:00:51 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Bos taurus
- Homo sapiens
- Phosphatidylinositol-4,5-bisphosphate 3-kinase
- Backer, J M.
- Hon, W C.
- Inbar, Y.
- Miled, N.
- Perisic, O.
- Schneidman-Duhovny, D.
- Williams, R L.
- Wolfson, H J.
- Yan, Y.
- Zvelebil, M.
- Alternative splicing
- Cancer
- Disease mutation
- Host-virus interaction
- Kinase
- Oncogenic mutation
- Phosphoinositide
- Phosphoinositide 3-kinase
- Phospholipid
- Phospholipid signalling
- Phosphorylation
- Polymorphism
- Sh2 domain
- Sh3 domain
- Signal transduction
- Transferase
- Ubl conjugation
