2ayp | pdb_00002ayp

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File:2ayp.png

Template:STRUCTURE 2ayp

Crystal Structure of CHK1 with an Indol Inhibitor

Template:ABSTRACT PUBMED 16242328

About this Structure

2AYP is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Lin NH, Xia P, Kovar P, Park C, Chen Z, Zhang H, Rosenberg SH, Sham HL. Synthesis and biological evaluation of 3-ethylidene-1,3-dihydro-indol-2-ones as novel checkpoint 1 inhibitors. Bioorg Med Chem Lett. 2006 Jan 15;16(2):421-6. Epub 2005 Oct 18. PMID:16242328 doi:10.1016/j.bmcl.2005.09.064

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