2rj7 | pdb_00002rj7

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File:2rj7.png

Template:STRUCTURE 2rj7

B-specific alpha-1,3-galactosyltransferase G176R S235G mutant (AABB) + UDPGal + Deoxy-acceptor

Template:ABSTRACT PUBMED 18192272

Disease

Known disease associated with this structure: Blood group, ABO system OMIM:[110300]

About this Structure

2RJ7 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Alfaro JA, Zheng RB, Persson M, Letts JA, Polakowski R, Bai Y, Borisova SN, Seto NO, Lowary TL, Palcic MM, Evans SV. ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes. J Biol Chem. 2008 Apr 11;283(15):10097-108. Epub 2008 Jan 11. PMID:18192272 doi:10.1074/jbc.M708669200

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