1s3v | pdb_00001s3v

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Template:STRUCTURE 1s3v

File:1s3v.png

Structure Determination of Tetrahydroquinazoline Antifolates in Complex with Human and Pneumocystis carinii Dihydrofolate Reductase: Correlations of Enzyme Selectivity and Stereochemistry

Template:ABSTRACT PUBMED 15039552

Disease

Known disease associated with this structure: Anemia, megaloblastic, due to DHFR deficiency (1) OMIM:[126060]

About this Structure

1S3V is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Cody V, Luft JR, Pangborn W, Gangjee A, Queener SF. Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry. Acta Crystallogr D Biol Crystallogr. 2004 Apr;60(Pt 4):646-55. Epub 2004, Mar 23. PMID:15039552 doi:https://dx.doi.org/10.1107/S0907444904002094

Page seeded by OCA on Tue Feb 17 04:52:30 2009

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OCA

[1] Cody V, Luft JR, Pangborn W, Gangjee A, Queener SF. Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry. Acta Crystallogr D Biol Crystallogr. 2004 Apr;60(Pt 4):646-55. Epub 2004, Mar 23. PMID:15039552 doi:https://dx.doi.org/10.1107/S0907444904002094

1s3v | pdb_00001s3v

Contents

Structure Determination of Tetrahydroquinazoline Antifolates in Complex with Human and Pneumocystis carinii Dihydrofolate Reductase: Correlations of Enzyme Selectivity and Stereochemistry

Disease

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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