1t2v | pdb_00001t2v

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File:1t2v.png

Template:STRUCTURE 1t2v

Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide

Template:ABSTRACT PUBMED 15133503

Disease

Known disease associated with this structure: Breast cancer-1 OMIM:[113705], Breast-ovarian cancer OMIM:[113705], Ovarian cancer OMIM:[113705], Papillary serous carcinoma of the peritoneum OMIM:[113705]

About this Structure

1T2V is a 10 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Williams RS, Lee MS, Hau DD, Glover JN. Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1. Nat Struct Mol Biol. 2004 Jun;11(6):519-25. Epub 2004 May 9. PMID:15133503 doi:https://dx.doi.org/10.1038/nsmb776

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