1iii | pdb_00001iii
From Proteopedia
CRYSTAL STRUCTURE OF THE TRANSTHYRETIN MUTANT TTR Y114C-DATA COLLECTED AT ROOM TEMPERATURE
Template:ABSTRACT PUBMED 12403615
Disease
Known disease associated with this structure: Amyloid polyneuropathy, several types OMIM:[176300], Amyloidosis, senile systemic OMIM:[176300], Carpal tunnel syndrome, familial OMIM:[176300], Dystransthyretinemic hyperthyroxinemia OMIM:[176300]
About this Structure
1III is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Eneqvist T, Olofsson A, Ando Y, Miyakawa T, Katsuragi S, Jass J, Lundgren E, Sauer-Eriksson AE. Disulfide-bond formation in the transthyretin mutant Y114C prevents amyloid fibril formation in vivo and in vitro. Biochemistry. 2002 Nov 5;41(44):13143-51. PMID:12403615
Page seeded by OCA on Tue Feb 17 05:09:38 2009
