1rtl | pdb_00001rtl

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Template:STRUCTURE 1rtl

File:1rtl.png

CRYSTAL STRUCTURE OF HCV NS3 PROTEASE DOMAIN: NS4A PEPTIDE COMPLEX WITH COVALENTLY BOUND PYRROLIDINE-5,5-TRANSLACTAM INHIBITOR

Template:ABSTRACT PUBMED 14627400

About this Structure

1RTL is a 4 chains structure of sequences from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

  1. Slater MJ, Amphlett EM, Andrews DM, Bamborough P, Carey SJ, Johnson MR, Jones PS, Mills G, Parry NR, Somers DO, Stewart AJ, Skarzynski T. Pyrrolidine-5,5-trans-lactams. 4. Incorporation of a P3/P4 urea leads to potent intracellular inhibitors of hepatitis C virus NS3/4A protease. Org Lett. 2003 Nov 27;5(24):4627-30. PMID:14627400 doi:10.1021/ol035826v

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