2vin | pdb_00002vin
From Proteopedia
FRAGMENT-BASED DISCOVERY OF MEXILETINE DERIVATIVES AS ORALLY BIOAVAILABLE INHIBITORS OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR
About this Structure
2VIN is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Frederickson M, Callaghan O, Chessari G, Congreve M, Cowan SR, Matthews JE, McMenamin R, Smith DM, Vinkovic M, Wallis NG. Fragment-based discovery of mexiletine derivatives as orally bioavailable inhibitors of urokinase-type plasminogen activator. J Med Chem. 2008 Jan 24;51(2):183-6. Epub 2007 Dec 29. PMID:18163548 doi:https://dx.doi.org/10.1021/jm701359z
Page seeded by OCA on Tue Feb 17 05:52:16 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- U-plasminogen activator
- Callaghan, O.
- Chessari, G.
- Congreve, M.
- Cowan, S R.
- Frederickson, M.
- Matthews, J E.
- Mcmenamin, R.
- Smith, D.
- Vinkovic, M.
- Wallis, N G.
- Blood coagulation
- Egf-like domain
- Fibrinolysis
- Glycoprotein
- Hydrolase
- Inhibitor
- Kringle
- Pharmaceutical
- Phosphorylation
- Plasminogen activation
- Polymorphism
- Protease
- Secreted
- Serine protease
- Urokinase-type plasminogen activator
- Zymogen
