3c6m | pdb_00003c6m

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Template:STRUCTURE 3c6m

File:3c6m.png

Crystal structure of human spermine synthase in complex with spermine and 5-methylthioadenosine

Template:ABSTRACT PUBMED 18367445

Disease

Known disease associated with this structure: Mental retardation, X-linked, Snyder-Robinson type OMIM:[300105], Smith-Magenis syndrome OMIM:[607642]

About this Structure

3C6M is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Wu H, Min J, Zeng H, McCloskey DE, Ikeguchi Y, Loppnau P, Michael AJ, Pegg AE, Plotnikov AN. Crystal structure of human spermine synthase: implications of substrate binding and catalytic mechanism. J Biol Chem. 2008 Jun 6;283(23):16135-46. Epub 2008 Mar 26. PMID:18367445 doi:https://dx.doi.org/10.1074/jbc.M710323200

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