1kw0 | pdb_00001kw0

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Template:STRUCTURE 1kw0

File:1kw0.png

Catalytic Domain of Human Phenylalanine Hydroxylase (Fe(II)) in Complex with Tetrahydrobiopterin and Thienylalanine

Template:ABSTRACT PUBMED 12126628

Disease

Known disease associated with this structure: Phenylketonuria OMIM:[612349], Hyperphenylalaninemia, mild OMIM:[612349]

About this Structure

1KW0 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Andersen OA, Flatmark T, Hough E. Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation. J Mol Biol. 2002 Jul 26;320(5):1095-108. PMID:12126628

Page seeded by OCA on Tue Feb 17 07:53:10 2009

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OCA

[1] Andersen OA, Flatmark T, Hough E. Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation. J Mol Biol. 2002 Jul 26;320(5):1095-108. PMID:12126628

1kw0 | pdb_00001kw0

Contents

Catalytic Domain of Human Phenylalanine Hydroxylase (Fe(II)) in Complex with Tetrahydrobiopterin and Thienylalanine

Disease

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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