3bet | pdb_00003bet

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File:3bet.png

Template:STRUCTURE 3bet

Crystal structure of the human carbonic anhydrase II in complex with STX 641 at 1.85 angstroms resolution

Template:ABSTRACT PUBMED 18260615

About this Structure

3BET is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Leese MP, Jourdan FL, Gaukroger K, Mahon MF, Newman SP, Foster PA, Stengel C, Regis-Lydi S, Ferrandis E, Di Fiore A, De Simone G, Supuran CT, Purohit A, Reed MJ, Potter BV. Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents. J Med Chem. 2008 Mar 13;51(5):1295-308. Epub 2008 Feb 9. PMID:18260615 doi:10.1021/jm701319c
  2. Eriksson AE, Jones TA, Liljas A. Refined structure of human carbonic anhydrase II at 2.0 A resolution. Proteins. 1988;4(4):274-82. PMID:3151019 doi:https://dx.doi.org/10.1002/prot.340040406
  3. Leese MP, Leblond B, Smith A, Newman SP, Di Fiore A, De Simone G, Supuran CT, Purohit A, Reed MJ, Potter BV. 2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity. J Med Chem. 2006 Dec 28;49(26):7683-96. PMID:17181151 doi:10.1021/jm060705x

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