3b92 | pdb_00003b92
From Proteopedia
Novel thio-based TACE inhibitors Part 2: Rational design, synthesis and SAR of thiol-contaning aryl sufones
About this Structure
3B92 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bandarage UK, Wang T, Come JH, Perola E, Wei Y, Rao BG. Novel thiol-based TACE inhibitors. Part 2: Rational design, synthesis, and SAR of thiol-containing aryl sulfones. Bioorg Med Chem Lett. 2008 Jan 1;18(1):44-8. Epub 2007 Nov 13. PMID:18054488 doi:10.1016/j.bmcl.2007.11.014
Page seeded by OCA on Tue Feb 17 08:02:37 2009
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Categories:
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- ADAM 17 endopeptidase
- Homo sapiens
- Wei, Y.
- Alternative splicing
- Aryl-sulfonamide
- Cleavage on pair of basic residue
- Glycoprotein
- Hydrolase
- Membrane
- Metal-binding
- Metalloprotease
- Notch signaling pathway
- Phosphorylation
- Protease
- Sh3-binding
- Tace inhibitor
- Tnf-alpha converting enzyme
- Transmembrane
- Zinc
- Zymogen