2i42 | pdb_00002i42

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Template:STRUCTURE 2i42

File:2i42.png

Crystal structure of Yersinia protein tyrosine phosphatase complexed with vanadate, a transition state analogue

About this Structure

2I42 is a 1 chain structure of sequence from Yersinia enterocolitica. Full crystallographic information is available from OCA.

Reference

  1. Denu JM, Lohse DL, Vijayalakshmi J, Saper MA, Dixon JE. Visualization of intermediate and transition-state structures in protein-tyrosine phosphatase catalysis. Proc Natl Acad Sci U S A. 1996 Mar 19;93(6):2493-8. PMID:8637902
  2. Schubert HL, Fauman EB, Stuckey JA, Dixon JE, Saper MA. A ligand-induced conformational change in the Yersinia protein tyrosine phosphatase. Protein Sci. 1995 Sep;4(9):1904-13. PMID:8528087
  3. Zhang ZY, Wang Y, Dixon JE. Dissecting the catalytic mechanism of protein-tyrosine phosphatases. Proc Natl Acad Sci U S A. 1994 Mar 1;91(5):1624-7. PMID:8127855

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