1pl0 | pdb_00001pl0

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:1pl0.png

Template:STRUCTURE 1pl0

Crystal structure of human ATIC in complex with folate-based inhibitor, BW2315U89UC

Template:ABSTRACT PUBMED 14966129

Disease

Known disease associated with this structure: AICA-ribosiduria due to ATIC deficiency OMIM:[601731]

About this Structure

1PL0 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Cheong CG, Wolan DW, Greasley SE, Horton PA, Beardsley GP, Wilson IA. Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates. J Biol Chem. 2004 Apr 23;279(17):18034-45. Epub 2004 Feb 13. PMID:14966129 doi:10.1074/jbc.M313691200

Page seeded by OCA on Tue Feb 17 08:19:06 2009

Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Cheong CG, Wolan DW, Greasley SE, Horton PA, Beardsley GP, Wilson IA. Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates. J Biol Chem. 2004 Apr 23;279(17):18034-45. Epub 2004 Feb 13. PMID:14966129 doi:10.1074/jbc.M313691200

1pl0 | pdb_00001pl0

Contents

Crystal structure of human ATIC in complex with folate-based inhibitor, BW2315U89UC

Disease

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools