2px6 | pdb_00002px6

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Template:STRUCTURE 2px6

File:2px6.png

Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat

Template:ABSTRACT PUBMED 17618296

Disease

Known disease associated with this structure: Autoimmune lymphoproliferative syndrome, type IA OMIM:[134637], Squamous cell carcinoma, burn scar-related, somatic OMIM:[134637], Autoimmune lymphoproliferative syndrome OMIM:[134637]

About this Structure

2PX6 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Pemble CW 4th, Johnson LC, Kridel SJ, Lowther WT. Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat. Nat Struct Mol Biol. 2007 Aug;14(8):704-9. Epub 2007 Jul 8. PMID:17618296 doi:10.1038/nsmb1265

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