2qqh | pdb_00002qqh
From Proteopedia
Structure of C8a-MACPF reveals mechanism of membrane attack in complement immune defense
Disease
Known disease associated with this structure: C8 deficiency, type I OMIM:[120950]
About this Structure
2QQH is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Hadders MA, Beringer DX, Gros P. Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense. Science. 2007 Sep 14;317(5844):1552-4. PMID:17872444 doi:317/5844/1552
Page seeded by OCA on Tue Feb 17 09:06:32 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
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- Homo sapiens
- Gros, P.
- Hadders, M A.
- Cleavage on pair of basic residue
- Complement alternate pathway
- Complement pathway
- Cytolysis
- Egf-like domain
- Glycoprotein
- Immune response
- Immune system
- Innate immunity
- Macpf
- Membrane attack complex
- Membrane perforation
- Membrane protein
- Polymorphism
- Secreted
