2ra0 | pdb_00002ra0

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File:2ra0.png

Template:STRUCTURE 2ra0

X-ray Structure of FXa in complex with 7-fluoroindazole

Template:ABSTRACT PUBMED 18159923

Disease

Known disease associated with this structure: Factor X deficiency OMIM:[227600]

About this Structure

2RA0 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Lee YK, Parks DJ, Lu T, Thieu TV, Markotan T, Pan W, McComsey DF, Milkiewicz KL, Crysler CS, Ninan N, Abad MC, Giardino EC, Maryanoff BE, Damiano BP, Player MR. 7-fluoroindazoles as potent and selective inhibitors of factor Xa. J Med Chem. 2008 Jan 24;51(2):282-97. Epub 2007 Dec 27. PMID:18159923 doi:10.1021/jm701217r

Page seeded by OCA on Tue Feb 17 09:26:31 2009

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