2an4 | pdb_00002an4

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Template:STRUCTURE 2an4

File:2an4.png

Structure of PNMT complexed with S-adenosyl-L-homocysteine and the acceptor substrate octopamine

Template:ABSTRACT PUBMED 16363801

Disease

Known disease associated with this structure: Hypertension, essential, 145500 (1) OMIM:[171190]

About this Structure

2AN4 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Gee CL, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL. Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis. Biochemistry. 2005 Dec 27;44(51):16875-85. PMID:16363801 doi:https://dx.doi.org/10.1021/bi051636b

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