1tqf | pdb_00001tqf
From Proteopedia
Template:ABSTRACT PUBMED 15566281
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| 1tqf, resolution 1.80Å (default scene) | |||||||||||||
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| Ligands: | 32P | ||||||||||||
| Gene: | BACE1, BACE (Homo sapiens) | ||||||||||||
| Activity: | Memapsin 2, with EC number 3.4.23.46 | ||||||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Crystal structure of human Beta secretase complexed with inhibitor
About this Structure
1TQF is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Coburn CA, Stachel SJ, Li YM, Rush DM, Steele TG, Chen-Dodson E, Holloway MK, Xu M, Huang Q, Lai MT, DiMuzio J, Crouthamel MC, Shi XP, Sardana V, Chen Z, Munshi S, Kuo L, Makara GM, Annis DA, Tadikonda PK, Nash HM, Vacca JP, Wang T. Identification of a small molecule nonpeptide active site beta-secretase inhibitor that displays a nontraditional binding mode for aspartyl proteases. J Med Chem. 2004 Dec 2;47(25):6117-9. PMID:15566281 doi:10.1021/jm049388p
Page seeded by OCA on Tue Feb 17 10:27:15 2009
