1rg2 | pdb_00001rg2

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Template:STRUCTURE 1rg2

File:1rg2.png

Crystal structure of human Tyrosyl-DNA Phosphodiesterase complexed with vanadate, octopamine, and tetranucleotide AGTA

Template:ABSTRACT PUBMED 14761185

Disease

Known disease associated with this structure: Spinocerebellar ataxia, autosomal recessive with axonal neuropathy OMIM:[607198]

About this Structure

1RG2 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Davies DR, Interthal H, Champoux JJ, Hol WG. Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes. J Med Chem. 2004 Feb 12;47(4):829-37. PMID:14761185 doi:10.1021/jm030487x

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