1nql | pdb_00001nql

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File:1nql.png

Template:STRUCTURE 1nql

Structure of the extracellular domain of human epidermal growth factor (EGF) receptor in an inactive (low pH) complex with EGF.

Template:ABSTRACT PUBMED 12620237

Disease

Known disease associated with this structure: Hypomagnesemia 4, renal OMIM:[131530]

About this Structure

1NQL is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Ferguson KM, Berger MB, Mendrola JM, Cho HS, Leahy DJ, Lemmon MA. EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization. Mol Cell. 2003 Feb;11(2):507-17. PMID:12620237

Page seeded by OCA on Tue Feb 17 11:35:32 2009

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OCA

[1] Ferguson KM, Berger MB, Mendrola JM, Cho HS, Leahy DJ, Lemmon MA. EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization. Mol Cell. 2003 Feb;11(2):507-17. PMID:12620237

1nql | pdb_00001nql

Contents

Structure of the extracellular domain of human epidermal growth factor (EGF) receptor in an inactive (low pH) complex with EGF.

Disease

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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