2duz | pdb_00002duz

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Template:STRUCTURE 2duz

File:2duz.png

Human Aldose Reductase complexed with inhibitor zopolrestat after 3 days soaking (3days_soaked_2)

Template:ABSTRACT PUBMED 16952371

About this Structure

2DUZ is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Steuber H, Zentgraf M, Gerlach C, Sotriffer CA, Heine A, Klebe G. Expect the unexpected or caveat for drug designers: multiple structure determinations using aldose reductase crystals treated under varying soaking and co-crystallisation conditions. J Mol Biol. 2006 Oct 13;363(1):174-87. Epub 2006 Aug 9. PMID:16952371 doi:https://dx.doi.org/10.1016/j.jmb.2006.08.011

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