2qx1 | pdb_00002qx1
From Proteopedia
Crystal structure of the complex between mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FABH) and decyl-COA disulfide
About this Structure
2QX1 is a 2 chains structure of sequences from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Sachdeva S, Musayev F, Alhamadsheh MM, Neel Scarsdale J, Tonie Wright H, Reynolds KA. Probing reactivity and substrate specificity of both subunits of the dimeric Mycobacterium tuberculosis FabH using alkyl-CoA disulfide inhibitors and acyl-CoA substrates. Bioorg Chem. 2008 Apr;36(2):85-90. Epub 2007 Dec 21. PMID:18096200 doi:10.1016/j.bioorg.2007.11.001
- Scarsdale JN, Kazanina G, He X, Reynolds KA, Wright HT. Crystal structure of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III. J Biol Chem. 2001 Jun 8;276(23):20516-22. Epub 2001 Mar 8. PMID:11278743 doi:10.1074/jbc.M010762200
- Musayev F, Sachdeva S, Scarsdale JN, Reynolds KA, Wright HT. Crystal structure of a substrate complex of Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FabH) with lauroyl-coenzyme A. J Mol Biol. 2005 Mar 11;346(5):1313-21. Epub 2005 Jan 20. PMID:15713483 doi:10.1016/j.jmb.2004.12.044
Page seeded by OCA on Tue Feb 17 12:10:35 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Beta-ketoacyl-acyl-carrier-protein synthase I
- Mycobacterium tuberculosis
- Alhamadsheh, M.
- Musayev, F.
- Reynolds, K A.
- Sachdeva, S.
- Scarsdale, J N.
- Wright, H T.
- Acyltransferase
- Cytoplasm
- Enzyme inhibitor complex
- Fatty acid biosynthesis
- Lipid synthesis
- Mechanism based inhibitor
- Multifunctional enzyme
- Myobacterium tuberculosis
- Structural basis for substrate specificity
- Transferase
