3ela | pdb_00003ela
From Proteopedia
Crystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factor
Disease
Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]
About this Structure
3ELA is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bjelke JR, Olsen OH, Fodje M, Svensson LA, Bang S, Bolt G, Kragelund BB, Persson E. Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity. J Biol Chem. 2008 Sep 19;283(38):25863-70. Epub 2008 Jul 17. PMID:18640965 doi:10.1074/jbc.M800841200
Page seeded by OCA on Tue Feb 17 12:17:26 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Coagulation factor VIIa
- Homo sapiens
- Bjelke, J R.
- Fodje, M.
- Svensson, L A.
- Allosteric regulation
- Allostery
- Alternative splicing
- Blood clotting
- Blood coagulation
- Calcium
- Cleavage on pair of basic residue
- Disease mutation
- Egf-like domain
- Exosite
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Hydroxylation
- Lipoprotein
- Membrane
- Palmitate
- Pharmaceutical
- Polymorphism
- Protease
- Secreted
- Serine protease
- Transmembrane
- Zymogen
