2zmm | pdb_00002zmm

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File:2zmm.png

Template:STRUCTURE 2zmm

Crystal structure of PTP1B-inhibitor complex

Disease

Known disease associated with this structure: Insulin resistance, susceptibility to OMIM:[176885]

About this Structure

2ZMM is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Wan ZK, Lee J, Hotchandani R, Moretto A, Binnun E, Wilson DP, Kirincich SJ, Follows BC, Ipek M, Xu W, Joseph-McCarthy D, Zhang YL, Tam M, Erbe DV, Tobin JF, Li W, Tam SY, Mansour TS, Wu J. Structure-based optimization of protein tyrosine phosphatase-1 B inhibitors: capturing interactions with arginine 24. ChemMedChem. 2008 Oct;3(10):1525-9. PMID:18798205 doi:10.1002/cmdc.200800188

Page seeded by OCA on Tue Feb 17 12:47:15 2009

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OCA

[1] Wan ZK, Lee J, Hotchandani R, Moretto A, Binnun E, Wilson DP, Kirincich SJ, Follows BC, Ipek M, Xu W, Joseph-McCarthy D, Zhang YL, Tam M, Erbe DV, Tobin JF, Li W, Tam SY, Mansour TS, Wu J. Structure-based optimization of protein tyrosine phosphatase-1 B inhibitors: capturing interactions with arginine 24. ChemMedChem. 2008 Oct;3(10):1525-9. PMID:18798205 doi:10.1002/cmdc.200800188

2zmm | pdb_00002zmm

Contents

Crystal structure of PTP1B-inhibitor complex

Disease

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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