2hx4 | pdb_00002hx4
From Proteopedia
Rat nNOS heme domain complexed with 4-N-(Nw-nitro-L-argininyl)-trans-4-hydroxyamino-L-proline amide
Template:ABSTRACT PUBMED 17425297
About this Structure
2HX4 is a 2 chains structure of sequences from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Seo J, Igarashi J, Li H, Martasek P, Roman LJ, Poulos TL, Silverman RB. Structure-based design and synthesis of N(omega)-nitro-L-arginine-containing peptidomimetics as selective inhibitors of neuronal nitric oxide synthase. Displacement of the heme structural water. J Med Chem. 2007 May 3;50(9):2089-99. Epub 2007 Apr 11. PMID:17425297 doi:10.1021/jm061305c
- Flinspach ML, Li H, Jamal J, Yang W, Huang H, Hah JM, Gomez-Vidal JA, Litzinger EA, Silverman RB, Poulos TL. Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase. Nat Struct Mol Biol. 2004 Jan;11(1):54-9. Epub 2003 Dec 29. PMID:14718923 doi:https://dx.doi.org/10.1038/nsmb704
Page seeded by OCA on Tue Feb 17 13:13:47 2009
