2k27 | pdb_00002k27

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File:2k27.png

Template:STRUCTURE 2k27

Solution structure of Human Pax8 Paired Box Domain

Template:ABSTRACT PUBMED 18829450

Disease

Known disease associated with this structure: Hypothyroidism, congenital, due to thyroid dysgenesis or hypoplasia OMIM:[167415]

About this Structure

2K27 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Codutti L, van Ingen H, Vascotto C, Fogolari F, Corazza A, Tell G, Quadrifoglio F, Viglino P, Boelens R, Esposito G. The solution structure of DNA-free Pax-8 paired box domain accounts for redox regulation of transcriptional activity in the pax protein family. J Biol Chem. 2008 Nov 28;283(48):33321-8. Epub 2008 Sep 30. PMID:18829450 doi:10.1074/jbc.M805717200

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