2g8o | pdb_00002g8o

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File:2g8o.png

Template:STRUCTURE 2g8o

High resolution structure of Escherichia coli thymidylate synthase ternary complex with dUMP and a cofactor analog, CB3717

Template:ABSTRACT PUBMED 16768437

About this Structure

2G8O is a 2 chains structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  1. Newby Z, Lee TT, Morse RJ, Liu Y, Liu L, Venkatraman P, Santi DV, Finer-Moore JS, Stroud RM. The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261. Biochemistry. 2006 Jun 20;45(24):7415-28. PMID:16768437 doi:10.1021/bi060152s

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OCA, Jaime Prilusky